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Isolation, stability and bioactivity of Jatropha curcas phorbol esters
Joy S Roach1, Rakshit K Devappa, Harinder P S Makkar
1Institute for Animal Production in the Tropics and Subtropics, 480b, University of Hohenheim, Stuttgart-70599, Germany.
Abstract:
Jatropha curcas seed oil, which can be utilized for biodiesel production upon transesterification, is also rich in phorbol esters (PEs). In this study, PEs from J. curcas oil (Jatropha factors C₁ and C₂ (purified to homogeneity), Jatropha factors C₃ and (C₄+C₅) (obtained as mixtures) and PE-rich extract (containing all the above stated Jatropha factors) were investigated. The concentrations of Jatropha PEs were expressed equivalent to Jatropha factor C₁. In the snail (Physa fontinalis) bioassay, the order of potency (EC₅₀, μg/L) was: PE-rich extract
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