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Updated: May 25, 2026

Implantation of the Syncardia Total Artificial Heart

Implantation of the Syncardia Total Artificial Heart

Published on: July 18, 2014

Experience with more than 100 total artificial heart implants.

Jack G Copeland¹, Hannah Copeland, Monica Gustafson

¹Department of Surgery, University of California San Diego, San Diego, CA 92103, USA. jackcope3@gmail.com

The Journal of Thoracic and Cardiovascular Surgery

|January 17, 2012

Summary

The SynCardia Total Artificial Heart provides a viable option for patients awaiting heart transplants, demonstrating improved survival rates and manageable complications for those ineligible for other therapies.

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Area of Science:

Cardiovascular Surgery
Medical Devices
Transplantation Medicine

Background:

The SynCardia Total Artificial Heart (TAH) is utilized globally as a bridge to cardiac transplantation.
101 patients within our program have received the SynCardia TAH.

Purpose of the Study:

To document the indications, safety, and efficacy of the SynCardia TAH in a large patient cohort.
To analyze outcomes for patients receiving the TAH as a bridge to transplant.

Main Methods:

Retrospective review and analysis of data for 101 patients who underwent SynCardia TAH implantation.
Data collected included preoperative condition, mortality, and morbidity.

Main Results:

From 1993-2009, 101 patients received the SynCardia TAH, predominantly (91%) as Interagency Registry for Mechanically Assisted Circulatory Support profile 1.

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Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart

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Implantation of Total Artificial Heart in Congenital Heart Disease

Implantation of Total Artificial Heart in Congenital Heart Disease

Published on: July 18, 2014

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Last Updated: May 25, 2026

Implantation of the Syncardia Total Artificial Heart

Implantation of the Syncardia Total Artificial Heart

Published on: July 18, 2014

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart

Published on: May 11, 2018

Implantation of Total Artificial Heart in Congenital Heart Disease

Implantation of Total Artificial Heart in Congenital Heart Disease

Published on: July 18, 2014

Mean support time was 87 days; survival to transplantation was 68.3%. Post-transplant survival at 1, 5, and 10 years was 76.8%, 60.5%, and 41.2%, respectively.

Adverse events included stroke (7.9%) and hemorrhage requiring reoperation (24.7%).

Conclusions:

The SynCardia TAH serves as a crucial alternative for patients not suitable for left ventricular assist devices, offering a chance for survival.
The device demonstrates a reasonable complication rate in carefully selected candidates who would otherwise face limited options, including hospice care.