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Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

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Hyperprolactinaemia and the empty sella.

M Thwin¹, B P Brophy

¹Department of Neurosurgery, Royal Adelaide Hospital, North Terrace, Adelaide, South Australia 5000, Australia. mthwin86@gmail.com

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia

|January 17, 2012

Summary

This summary is machine-generated.

Empty sella syndrome, a condition affecting the sella turcica, may be linked to hyperprolactinemia. This case report highlights a patient with elevated prolactin levels and empty sella diagnosed via MRI.

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Area of Science:

Endocrinology
Neuroimaging
Radiology

Background:

Hyperprolactinemia is an endocrine disorder characterized by elevated serum prolactin levels.
Empty sella is a radiological diagnosis of a deformed and enlarged sella turcica, often without intrinsic pituitary pathology.
The relationship between empty sella syndrome and hyperprolactinemia remains incompletely understood.

Observation:

A patient presented with symptoms of meningeal irritation and a history of galactorrhea.
The patient exhibited elevated serum prolactin levels.
Magnetic Resonance Imaging (MRI) confirmed the diagnosis of empty sella.

Findings:

The patient was diagnosed with hyperprolactinemia.
Empty sella syndrome was identified as a concurrent radiological finding.
The case suggests a potential association between these two conditions.

Implications:

Further research is warranted to elucidate the role of empty sella syndrome in the pathogenesis of hyperprolactinemia.
This case underscores the importance of considering endocrine evaluation in patients with empty sella.
Understanding this association may improve diagnostic and therapeutic strategies for patients with unexplained hyperprolactinemia.