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Updated: May 25, 2026

Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis

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Aggressive angiomyxoma: an unusual presentation.

Junzu Geng¹, Bofeng Cao, Liping Wang

¹The Image Center of Yantai Yuhuangding Hospital, Shandong Province, China. gengjz001@126.com

Korean Journal of Radiology

|January 17, 2012

Summary

Aggressive angiomyxoma, a rare tumor, typically recurs locally but does not metastasize. This case report details aggressive angiomyxoma with venous invasion and pulmonary metastases, suggesting a need to re-evaluate its nonmetastasizing nature.

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Area of Science:

Oncology
Pathology
Vascular Biology

Background:

Aggressive angiomyxoma is a rare mesenchymal tumor.
It is known for slow growth and local recurrence.
It is generally considered nonmetastasizing.

Observation:

A case of recurrent aggressive angiomyxoma is presented.
The tumor invaded major veins, including the inferior vena cava and right atrium.
Pulmonary metastases were observed.

Findings:

This case demonstrates aggressive angiomyxoma with extensive vascular invasion.
The presence of pulmonary metastases challenges the established understanding of the tumor's behavior.
This highlights the potential for aggressive metastatic spread.

Keywords:

Aggressive angiomyxoma Computed tomography Histopathology Inferior vena cava Pulmonary metastases

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Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis

Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis

Published on: May 1, 2015

Implications:

The findings suggest a need to re-evaluate the classification and metastatic potential of aggressive angiomyxoma.
Further research is warranted to understand the mechanisms driving metastasis in rare cases.
Clinical management strategies may need to consider the possibility of distant spread.