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Published on: August 4, 2017
Microsponges: A novel strategy for drug delivery system
Santanu Kaity1, Sabyasachi Maiti, Ashoke Kumar Ghosh
1Department of Pharmaceutics, Gupta College of Technological Sciences, Ashram More, G.T.Road, Asansol-713 301, West Bengal, India.
Journal of Advanced Pharmaceutical Technology & Research
|January 17, 2012
Summary
Polymeric microsponges are versatile drug delivery systems. These porous microspheres enhance drug stability, reduce side effects, and control release for topical and oral administration.
Area of Science:
- Polymer science and drug delivery systems.
Background:
- Microsponges are porous, polymeric microspheres with a sponge-like structure.
- They possess a large porous surface area, enabling sustained release of entrapped substances.
Purpose of the Study:
- To highlight the characteristics and applications of microsponge technology.
- To emphasize their role as a versatile drug delivery vehicle.
Main Methods:
- Characterization of microsponge properties, including porosity and surface area.
- Incorporation of active pharmaceutical ingredients into microsponge formulations.
- Evaluation of drug release profiles and stability.
Main Results:
- Microsponges demonstrate favorable characteristics for drug delivery.
- They can encapsulate a wide range of substances for various formulations.
- Sustained drug release is achieved due to the porous structure.
Conclusions:
- Microsponge technology offers an efficient method for drug delivery.
- It enhances drug stability, minimizes side effects, and modifies release kinetics.
- Applications span topical and oral administration routes.
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