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Andropausal symptoms in men with Type 2 diabetes
1Department of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan. sayarinapm@hotmail.com
Diabetic Medicine : a Journal of the British Diabetic Association
|January 18, 2012
Summary
Men with Type 2 diabetes experience more andropausal symptoms, including sleep issues and erectile dysfunction. Diabetic complications significantly worsen these symptoms, highlighting the need for targeted care.
Area of Science:
- Endocrinology
- Diabetology
- Men's Health
Background:
- Type 2 diabetes is associated with lower serum androgen levels.
- Andropausal symptoms (sleep disturbance, depression, erectile dysfunction, lower urinary tract symptoms) are common in aging men.
- Limited research exists on the simultaneous comparison of these symptoms between men with and without Type 2 diabetes.
Purpose of the Study:
- To compare the prevalence and severity of andropausal symptoms in men with Type 2 diabetes versus those without.
- To investigate the relationship between andropausal symptoms and anthropometric factors in diabetic patients.
- To assess the impact of diabetic complications on andropausal symptom scores.
Main Methods:
- Cross-sectional study comparing 296 men with Type 2 diabetes and 267 controls.
- Utilized validated questionnaires: Pittsburgh Sleep Quality Index (PSQI), Self-Rating Depression Scale (SRDS), International Index of Erectile Function (IIEF), and International Prostate Symptom Score (IPSS).
- Analyzed correlations with anthropometric data and compared scores based on the presence of diabetic complications.
Main Results:
- Men with Type 2 diabetes reported significantly higher scores for PSQI, SRDS, and IPSS, and lower scores for IIEF compared to controls.
- Higher PSQI scores were observed in patients with neuropathy.
- Advanced retinopathy was linked to higher SRDS and lower IIEF scores. Cardiovascular disease correlated with lower IIEF and higher IPSS.
Conclusions:
- Type 2 diabetes is associated with a higher prevalence of andropausal symptoms.
- Diabetic complications, including neuropathy, retinopathy, and cardiovascular disease, exacerbate these symptoms.
- These findings underscore the importance of screening for andropausal symptoms in men with Type 2 diabetes, particularly those with complications.
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