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Related Experiment Video

Updated: May 25, 2026

Vascular Gene Transfer from Metallic Stent Surfaces Using Adenoviral Vectors Tethered through Hydrolysable Cross-linkers

Vascular Gene Transfer from Metallic Stent Surfaces Using Adenoviral Vectors Tethered through Hydrolysable Cross-linkers

Published on: August 12, 2014

Carotid stenting versus endarterectomy.

David Doig¹, Martin M Brown

¹Institute of Neurology, University College London, London WC1N 3BG, United Kingdom. martin.brown@ucl.ac.uk

Annual Review of Medicine

|January 18, 2012

Summary

Carotid endarterectomy is the standard for symptomatic carotid stenosis, but angioplasty and stenting offer alternatives. Stenting has risks but may be suitable for select patients.

Area of Science:

Neurology
Vascular Surgery
Interventional Cardiology

Background:

Carotid endarterectomy (CEA) became standard after NASCET/ECST trials for symptomatic carotid artery stenosis.
Carotid artery stenting (CAS) emerged as an alternative, offering potential benefits like local anesthesia.

Purpose of the Study:

To compare the efficacy and safety of CEA versus CAS for secondary stroke prevention.
To evaluate the current role of CEA and CAS in managing symptomatic carotid artery stenosis.

Main Methods:

Pooled analysis of randomized controlled trials comparing CEA and CAS.
Review of outcomes including stroke, death, myocardial infarction, and cranial nerve palsy.

Main Results:

Related Experiment Videos

Last Updated: May 25, 2026

Vascular Gene Transfer from Metallic Stent Surfaces Using Adenoviral Vectors Tethered through Hydrolysable Cross-linkers

Vascular Gene Transfer from Metallic Stent Surfaces Using Adenoviral Vectors Tethered through Hydrolysable Cross-linkers

Published on: August 12, 2014

CAS showed a higher rate of stroke or death compared to CEA.

CAS demonstrated a lower incidence of myocardial infarction and cranial nerve palsy.

Conclusions:

Carotid endarterectomy with optimal drug therapy remains the gold standard for 70%-99% symptomatic internal carotid artery stenosis.
Carotid artery stenting may be a viable option for younger patients or those unsuitable for CEA.