Related Experiment Video
Updated: Feb 26, 2026
Using a 1064-nm Picosecond Neodymium-Doped Yttrium Aluminum Garnet Laser for Periorbital Hyperpigmentation
Published on: May 23, 2025
[Unsuccessful treatment with OK-432 picibanil for orbital lymphangioma]
A Lanuza García1, R Bañón Navarro, A Llorca Cardeñosa
1Servicio de Oftalmología, Hospital General de Castellón, Castellón, España. lanuza.amp@gva.es
Introduction:
Lymphangioma is a malformation of the lymphatic system. The classic approach is surgery. We report a case of orbital lymphangioma in a girl who was given OK-432 to avoid surgery and its complications.
Discussion:
OK-432 is a lyophilized mixture of group A Streptococcus pyogenes which produces a fibrosis limited to the lesion with a high cure rate. The main advantages are the easy intra-lesional application. with no scars and or damage of closed areas. Its main disadvantage is a significant local inflammatory reaction.
