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Related Concept Videos

Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution01:25

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion01:20

Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion

Drug metabolism, a critical process in the liver, involves two primary phases: Phase I reactions and Phase II conjugation. Obesity introduces significant alterations in this metabolic process, primarily due to fatty infiltration of the liver, leading to conditions such as nonalcoholic fatty liver disease (NAFLD). This condition can modify the activities of both Phase I and II enzymes, impacting how drugs are metabolized in obese patients.Phase I metabolism sees variable effects across...
Type II Diabetes I: Introduction01:26

Type II Diabetes I: Introduction

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance, in which target tissues such as the liver, muscle, and adipose tissue respond poorly to insulin. It is also associated with inadequate compensatory insulin secretion, where pancreatic β-cells fail to produce sufficient insulin. Together, these abnormalities lead to persistent hyperglycemia.EtiologyT2DM develops through a complex interaction of genetic predisposition and environmental or...
Bulimia Nervosa01:30

Bulimia Nervosa

Bulimia nervosa is a complex and severe eating disorder characterized by a cyclical pattern of binge-and-purge eating pattern. It generally involves an episode of binge eating, followed by compensatory behaviors such as vomiting, excessive exercise, laxative use, or fasting, to prevent weight gain. Despite often maintaining a normal weight, individuals with bulimia are intensely preoccupied with their body image and harbor an overwhelming fear of gaining weight. This can contribute to the...

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Updated: May 25, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
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Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

Obesity: an emerging disease.

A M Ogunbode1, Mma Ladipo, I O Ajayi

  • 1Department of Family Medicine, University College Hospital, Ibadan, Nigeria. jamchose@yahoo.co.uk

Nigerian Journal of Clinical Practice
|January 18, 2012
PubMed
Summary

Obesity is a growing global health issue, particularly in developing nations, driven by lifestyle changes. Understanding its causes, co-morbidities, and management is crucial for public health.

Area of Science:

  • Public Health
  • Epidemiology
  • Metabolic Disorders

Background:

  • Obesity is an emerging global health concern, especially in developing countries.
  • Increasing westernization and lifestyle changes contribute to rising obesity rates.
  • Obesity has multifactorial etiology, involving genetic and environmental factors.

Purpose of the Study:

  • To provide a comprehensive overview of obesity.
  • To review the current knowledge on obesity, its causes, and consequences.
  • To highlight the need for improved understanding and management of obesity in developing nations.

Main Methods:

  • Extensive literature review utilizing original articles, review articles, and textbooks.
  • Searched databases and internet search engines for relevant studies.

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  • Included literature published between 1993 and 2008.
  • Main Results:

    • Obesity is classified using Body Mass Index (BMI) and waist-hip ratio.
    • Associated co-morbidities include diabetes mellitus, hypertension, osteoarthritis, and infertility.
    • Limited specific data on obesity prevalence and management in Nigeria was noted.

    Conclusions:

    • A comprehensive literature review is essential to enhance knowledge on obesity in developing countries.
    • Improved understanding is needed for effective prevention and management strategies.
    • Further research is warranted, particularly in regions with limited data like Nigeria.