Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Nicotinamide Supplementation and Primary Open-Angle Glaucoma in Patients With Ocular Hypertension.

JAMA ophthalmology·2026

Same author

Effect of intraocular pressure control on visual field progression in the HORIZON trial.

Ophthalmology. Glaucoma·2026

Same author

Evaluation of the Deep Reality Viewer for teaching slit-lamp examination of the anterior segment and the optic nerve head.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2026

Same author

Is ophthalmology a pain-free career? A systematic review and meta-analysis of musculoskeletal pain among ophthalmologists.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2026

Same author

Comparative Outcomes of Standalone Xen63 Gel Stent and Preserflo Microshunt Implantation: A Multicenter Study.

Clinical ophthalmology (Auckland, N.Z.)·2026

Same author

The Flip Sides of Interventional Glaucoma.

Ophthalmology. Glaucoma·2026

Search research articles

Related Experiment Video

Updated: May 25, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

Micro-invasive glaucoma surgery: current perspectives and future directions.

Hady Saheb¹, Iqbal Ike K Ahmed

¹Department of Ophthalmology, McGill University Health Center, Montreal, Quebec, Canada. hady.el-saheb@mail.mcgill.ca

Current Opinion in Ophthalmology

|January 18, 2012

Summary

This summary is machine-generated.

Micro-invasive glaucoma surgery (MIGS) offers reduced intraocular pressure (IOP) and medication dependence with a good safety profile. Evidence is growing for MIGS, clarifying its role alongside traditional glaucoma surgeries.

Related Experiment Videos

Last Updated: May 25, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

Area of Science:

Ophthalmology
Glaucoma Surgery
Medical Devices

Background:

Increasing interest and availability of micro-invasive glaucoma surgery (MIGS) procedures.
Need for sound, peer-reviewed evidence to support the rise of MIGS.
Importance of understanding MIGS within the broader glaucoma treatment landscape.

Purpose of the Study:

Define micro-invasive glaucoma surgery (MIGS).
Review recent publications on MIGS procedures.
Discuss future directions for MIGS research and application.

Main Methods:

Review of pivotal trials and initial results of various MIGS devices.
Comparison of MIGS procedures with traditional surgeries (e.g., phacoemulsification, trabeculectomy).
Analysis of studies on device placement, gonioscopy, cost-effectiveness, and quality of life.

Main Results:

Trabecular micro-bypass stents (iStent) showed improved unmedicated IOP control compared to phacoemulsification alone.
Newer MIGS devices (iStent inject, Hydrus, CyPass) demonstrate reduced postoperative IOP.
Phaco-Trabectome and excimer laser trabeculostomy show comparable success rates to other procedures with potentially fewer complications.

Conclusions:

MIGS procedures effectively reduce intraocular pressure (IOP) and medication reliance.
MIGS exhibit an excellent safety profile.
The role of MIGS in glaucoma treatment algorithms is evolving and distinct from more invasive surgeries.