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Bacterial Phylum Chlamydiae

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Sexually Transmitted Infections01:26

Sexually Transmitted Infections

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Updated: May 25, 2026

Forward Genetic Approaches in Chlamydia trachomatis
09:03

Forward Genetic Approaches in Chlamydia trachomatis

Published on: October 23, 2013

Interventions to increase rescreening for repeat chlamydial infection.

Rebecca Guy1, Jane Hocking, Nicola Low

  • 1The Kirby Institute (formerly the National Centre in HIV Epidemiology and Clinical Research), University of New South Wales, Sydney, Australia. Rguy@kirby.unsw.edu.au

Sexually Transmitted Diseases
|January 18, 2012
PubMed
Summary
This summary is machine-generated.

Repeat Chlamydia trachomatis infections are common. Interventions like mailed screening kits and reminder systems can significantly increase rescreening rates, helping to prevent sequelae.

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Live-Cell Forward Genetic Approach to Identify and Isolate Developmental Mutants in Chlamydia trachomatis
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Published on: June 10, 2020

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Last Updated: May 25, 2026

Forward Genetic Approaches in Chlamydia trachomatis
09:03

Forward Genetic Approaches in Chlamydia trachomatis

Published on: October 23, 2013

Live-Cell Forward Genetic Approach to Identify and Isolate Developmental Mutants in Chlamydia trachomatis
10:32

Live-Cell Forward Genetic Approach to Identify and Isolate Developmental Mutants in Chlamydia trachomatis

Published on: June 10, 2020

Area of Science:

  • Public Health
  • Infectious Diseases
  • Health Services Research

Background:

  • Repeat Chlamydia trachomatis infections pose significant health risks and sequelae.
  • Despite guidelines, Chlamydia trachomatis rescreening rates within 3 months post-treatment are low.
  • A systematic review was conducted to evaluate interventions aimed at increasing Chlamydia trachomatis rescreening.

Purpose of the Study:

  • To systematically review and meta-analyze studies comparing Chlamydia trachomatis rescreening rates.
  • To identify effective interventions for increasing patient rescreening after Chlamydia trachomatis treatment.

Main Methods:

  • Systematic literature search of Medline, EMBASE, and conference websites (2000-2010).
  • Inclusion of randomized controlled trials (RCTs) and controlled observational studies.
  • Meta-analysis to calculate the relative risk (RR) of interventions on rescreening rates.

Main Results:

  • Eight RCTs and four controlled observational studies were identified.
  • Ma性iled screening kits demonstrated a positive effect on rescreening (RR 1.30).
  • Reminder systems showed promise, with one RCT indicating a substantial RR of 9.67 for reminders alone.

Conclusions:

  • Ma性iled screening kits are an effective strategy for increasing Chlamydia trachomatis rescreening.
  • Reminder systems show potential for improving rescreening adherence.
  • Motivational interviewing warrants further investigation as an intervention strategy.