Related Experiment Video
Updated: May 25, 2026
07:34
Microsurgical Venous Pouch Arterial-Bifurcation Aneurysms in the Rabbit Model: Technical Aspects
Published on: May 11, 2011
A clinical and histopathologic study of jugular bulb abnormalities
David R Friedmann1, Jan Eubig, Leon S Winata
1Department of Otolaryngology, New York University School of Medicine, New York, 10016, USA.
Archives of Otolaryngology--Head & Neck Surgery
|January 18, 2012
Summary
Jugular bulb abnormalities can erode inner ear structures, but half of affected patients are asymptomatic. Vestibular evoked myogenic potential (VEMP) testing aids in diagnosis.
Area of Science:
- Otolaryngology
- Neurotology
- Radiology
Background:
- Jugular bulb abnormalities (JBAs) are rare conditions that can affect the inner ear.
- Understanding the clinical and histologic consequences of JBAs is crucial for patient management.
Purpose of the Study:
- To define the clinical presentation of jugular bulb abnormalities (JBAs).
- To explore the histologic sequelae of inner ear dehiscence caused by JBAs.
Main Methods:
- Retrospective review of 30 patients with radiologic evidence of inner ear dehiscence due to JBAs.
- Evaluation of 1579 temporal bone specimens for JBA-related consequences.
- Computed tomography (CT) and magnetic resonance imaging (MRI) were used for imaging analysis.
Main Results:
- JBA-associated inner ear dehiscence was identifiable on CT but not MRI.
- The vestibular aqueduct was most frequently eroded (25 patients), followed by the facial nerve (5) and posterior semicircular canal (4).
- Half of the patients (15) were asymptomatic; VEMP testing was positive in 8/12 patients with dehiscence.
Conclusions:
- JBAs can erode into the vestibular aqueduct, facial nerve, and posterior semicircular canal.
- Symptoms like pulsatile tinnitus, vertigo, or hearing loss may occur, but many patients remain asymptomatic.
- Dehiscence of the vestibular aqueduct rarely leads to endolymphatic hydrops; VEMP testing is useful for diagnosis.
Related Concept Videos
01:21Aneurysm II: Clinical Manifestations and Diagnostic Studies
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
01:20Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
01:19Veins of Head and Neck
The blood drainage from the head and neck is primarily managed by three pairs of veins: the external jugular, internal jugular, and vertebral veins. The external jugular veins drain superficial scalp and face structures, passing over the sternocleidomastoid muscles to empty into the subclavian veins.
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
01:22Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
01:22Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
01:23Mitral Regurgitation II: Clinical Features and Diagnostic Tests
Mitral regurgitation (MR) is a valvular heart disorder in which the mitral valve fails to close tightly, allowing blood to leak backward into the heart. Understanding the clinical manifestations, assessment, diagnostic findings, and medical management of MR is crucial to effectively managing affected patients.Clinical Manifestations of Mitral RegurgitationMitral regurgitation can be acute or chronic, each presenting differently and requiring different approaches:1. Acute Mitral...