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Microbiota of the Large Intestine

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The large intestine hosts the most densely populated microbial ecosystem in the human body. This complex community primarily consists of anaerobic bacteria, with Bacillota (formerly Firmicutes) and Bacteroidota (formerly Bacteroidetes) as the predominant groups. The distribution of these microbes varies along different sections of the large intestine, influenced by local environmental factors such as oxygen availability and nutrient composition.The cecum, located at the beginning of the large...

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Related Experiment Video

Updated: May 25, 2026

Strategies to Enhance Cultivation of Anaerobic Bacteria from Gastrointestinal Tract of Chicken

Strategies to Enhance Cultivation of Anaerobic Bacteria from Gastrointestinal Tract of Chicken

Published on: May 10, 2024

Intestinal microbiota associated with differential feed conversion efficiency in chickens.

Dragana Stanley¹, Stuart E Denman, Robert J Hughes

¹CSIRO Livestock Industries, Australian Animal Health Laboratories, Private Bag 24, Geelong, Victoria, 3220, Australia. Dana.Stanley@csiro.au

Applied Microbiology and Biotechnology

|January 18, 2012

Summary

This summary is machine-generated.

Chicken gut microbiota impacts feed efficiency. Researchers found specific cecal bacteria linked to growth performance, suggesting prebiotics and probiotics could enhance animal production.

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Published on: February 20, 2015

Area of Science:

Animal Science
Microbiology
Agricultural Science

Background:

Gastrointestinal tract microbiota influences energy extraction from diets, as shown in model systems.
Feed conversion efficiency is critical in intensive animal production, impacting profitability.
Variability in broiler chicken growth performance under identical conditions suggests underlying biological differences.

Purpose of the Study:

To investigate correlations between gastrointestinal tract microbiota composition and energy utilization in chickens.
To identify specific bacterial species in broiler chickens associated with high and low feed conversion capabilities.
To explore potential microbial targets for improving animal growth performance in the poultry industry.

Main Methods:

Analysis of cecal and jejunal microbiota populations in broiler chickens exhibiting extreme feed conversion ratios.
Sequencing and comparative analysis of microbial communities to identify differentially abundant bacterial species.
Statistical analysis to determine significant differences in microbial populations between high and low performing birds.

Main Results:

Jejunal microbiota was dominated by Lactobacillus, with no significant differences observed between performance groups.
Cecal microbiota exhibited higher diversity, with 24 unclassified bacterial species showing significant differential abundance.
These differentially abundant cecal bacteria are potential candidates influencing feed conversion efficiency in chickens.

Conclusions:

Cecal microbiota composition, unlike jejunal microbiota, is associated with feed conversion capabilities in broiler chickens.
Specific bacterial species in the cecum may play a crucial role in modulating energy utilization and growth performance.
Targeted modulation of these identified bacterial populations using prebiotics or probiotics could enhance poultry production efficiency.