Related Experiment Video

Updated: May 25, 2026

Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure
09:38

Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure

Published on: August 11, 2017

Methods of resistance to epidermal growth factor receptor inhibition in glioblastoma multiforme

Ricardo J Komotar, Robert M Starke, E Sander Connolly

    Neurosurgery
    |January 19, 2012
    PubMed
    Abstract

    No abstract available in PubMed .

    More Related Videos

    A Simple Guide Screw Method for Intracranial Xenograft Studies in Mice
    08:11

    A Simple Guide Screw Method for Intracranial Xenograft Studies in Mice

    Published on: September 26, 2011

    Flow Cytometry-based Drug Screening System for the Identification of Small Molecules That Promote Cellular Differentiation of Glioblastoma Stem Cells
    10:28

    Flow Cytometry-based Drug Screening System for the Identification of Small Molecules That Promote Cellular Differentiation of Glioblastoma Stem Cells

    Published on: January 10, 2018

    Related Experiment Videos

    Last Updated: May 25, 2026

    Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure
    09:38

    Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure

    Published on: August 11, 2017

    A Simple Guide Screw Method for Intracranial Xenograft Studies in Mice
    08:11

    A Simple Guide Screw Method for Intracranial Xenograft Studies in Mice

    Published on: September 26, 2011

    Flow Cytometry-based Drug Screening System for the Identification of Small Molecules That Promote Cellular Differentiation of Glioblastoma Stem Cells
    10:28

    Flow Cytometry-based Drug Screening System for the Identification of Small Molecules That Promote Cellular Differentiation of Glioblastoma Stem Cells

    Published on: January 10, 2018

    Related Concept Videos

    Mitogens and the Cell Cycle02:38

    Mitogens and the Cell Cycle

    Mitogens and their receptors play a crucial role in controlling the progression of the cell cycle. However, the loss of mitogenic control over cell division leads to tumor formation. Therefore, mitogens and mitogen receptors play an important role in cancer research. For instance, the epidermal growth factor (EGF) - a type of mitogen and its transmembrane receptor (EGFR), decides the fate of the cell's proliferation. When EGF binds to EGFR, a member of the ErbB family of tyrosine kinase...
    Treatment Resistant Cancers02:56

    Treatment Resistant Cancers

    Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...

    Articles linked to this work by shared authors, journal, and citation graph.

    Curative treatment for low-grade arteriovenous malformations.

    Journal of neurointerventional surgery·2019

    Hyperemia in subarachnoid hemorrhage patients is associated with an increased risk of seizures.

    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism·2019

    Detection of Brain Activation in Unresponsive Patients with Acute Brain Injury.

    The New England journal of medicine·2019

    Low hemoglobin and hematoma expansion after intracerebral hemorrhage.

    Neurology·2019

    Medical Treatment Failure for Symptomatic Vasospasm After Subarachnoid Hemorrhage Threatens Long-Term Outcome.

    Stroke·2019

    Common Data Elements for Unruptured Intracranial Aneurysms and Aneurysmal Subarachnoid Hemorrhage: Recommendations from the Working Group on Hospital Course and Acute Therapies-Proposal of a Multidisciplinary Research Group.

    Neurocritical care·2019

    Diffusion Anisotropy Predicts Directional Progression After Complete Resection of Frontal Glioblastoma.

    Neurosurgery·2026

    Direct Oral Anticoagulant Plus Single Versus Dual Antiplatelet Therapy After Carotid Artery Stenting: A Multicenter Propensity-Matched Cohort Study.

    Neurosurgery·2026

    Days at Home After Traumatic Spinal Cord Injury: An Interpretable Patient-Centered Outcome From Administrative Health Data.

    Neurosurgery·2026

    Preinjury Statin Therapy and Outcomes After Traumatic Brain Injury.

    Neurosurgery·2026

    Simpson Grading and Risk of Recurrence in 4074 Meningioma Patients With Gross Total Resection.

    Neurosurgery·2026

    Randomized Trial of Burr-Hole Surgery With or Without Irrigation for Chronic Subdural Hematoma: Impact of Postoperative Pneumocephalus on Recurrence.

    Neurosurgery·2026
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies
    Jove
    Visualize
    Contact Us