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Related Concept Videos

Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Essential Minerals for Bone Health01:31

Essential Minerals for Bone Health

The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
The Functions of the Skeletal System01:22

The Functions of the Skeletal System

The most apparent functions of the skeletal system are support, protection, and movement. However, bone tissue also performs several other critical metabolic functions. For one, the bone matrix acts as a reservoir for a number of minerals important to the functioning of the body, especially calcium and phosphorus. These minerals, present in the bone tissue, can be released back into the bloodstream when required. Calcium ions, for example, are essential for muscle contractions and controlling...
Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...

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Related Experiment Video

Updated: May 25, 2026

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
07:56

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Published on: January 29, 2018

Bone health nutrition issues in aging.

Karen Plawecki1, Karen Chapman-Novakofski

  • 1Division of Nutritional Sciences, University of Illinois at Urbana-Champaign, 61801, USA. kmc@illinois.edu

Nutrients
|January 19, 2012
PubMed
Summary

Dietary and supplemental calcium and vitamin D interventions show positive effects on bone health in aging populations. Food-based and educational strategies are particularly effective, with lower economic impact and fewer side effects.

Keywords:
agingbonevitamin Dcalcium

Related Experiment Videos

Last Updated: May 25, 2026

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
07:56

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Published on: January 29, 2018

Area of Science:

  • Gerontology
  • Nutritional Science
  • Bone Metabolism

Background:

  • Bone health is a critical concern in aging populations.
  • Current research on nutrition and bone health in aging primarily focuses on calcium and vitamin D, but evidence remains inconclusive.
  • Understanding effective interventions is vital for maintaining bone integrity in older adults.

Purpose of the Study:

  • To systematically review the impact of dietary and supplemental calcium and vitamin D interventions on bone health in aging individuals over the past decade.
  • To evaluate the effectiveness of various nutritional and educational strategies.
  • To identify interventions with favorable economic and safety profiles.

Main Methods:

  • A systematic literature review was conducted using keywords related to diet, nutrition, bone health, calcium, and vitamin D.
  • Search limits included the aging population and English-language publications.
  • Papers were screened and analyzed for relevance and findings.

Main Results:

  • A positive effect on bone health was observed for both dietary and supplemental calcium and vitamin D interventions.
  • Food-based interventions and educational strategies demonstrated significant benefits.
  • These interventions were associated with less economic impact and a lower risk of physiological side effects compared to other approaches.

Conclusions:

  • Dietary and supplemental calcium and vitamin D interventions can positively impact bone health in aging.
  • Food-based and educational strategies offer effective, low-cost, and safe approaches to support bone health in older adults.
  • Further research should consider potential publishing biases and explore the long-term efficacy of these interventions.