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Published on: November 1, 2019
Dietary polyphenols and obesity.
Mohsen Meydani1, Syeda T Hasan
1Vascular Biology Laboratory, Jean Mayer USDA- Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA.
Nutrients
|January 19, 2012
Summary
Natural polyphenols show promise in combating obesity and related metabolic disorders by influencing energy expenditure. These compounds offer potential complementary strategies for weight management beyond traditional diet and exercise.
Area of Science:
- Nutritional Science
- Biochemistry
- Public Health
Background:
- Overweight and obesity are significant public health threats linked to metabolic disorders.
- Current weight loss methods often yield slow or disappointing results.
- Natural bioactive phytochemicals are gaining attention for their health benefits, including chronic disease prevention.
Purpose of the Study:
- To review the efficacy of specific polyphenols in modulating obesity and associated disorders.
- To explore the potential of polyphenols as complementary agents for weight management.
Main Methods:
- Review of existing literature on polyphenols, including cell cultures, animal models, and human studies.
- Focus on specific polyphenols: catechins, anthocyanins, resveratrol, and curcumin.
- Analysis of their effects on energy metabolism, adiposity, and obesity pathways.
Main Results:
- Polyphenols modulate physiological and molecular pathways involved in energy metabolism and adiposity.
- Evidence suggests in vivo beneficial effects of polyphenols on obesity.
- These compounds may aid in the up-regulation of energy expenditure.
Conclusions:
- Specific polyphenols demonstrate potential in managing obesity and related metabolic conditions.
- Polyphenols can serve as complementary agents to traditional weight management strategies.
- Further research supports their role in public health initiatives against obesity.
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