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Updated: May 25, 2026

A Multi-Electrode Array Platform for Modeling Epilepsy Using Human Pluripotent Stem Cell-Derived Brain Assembloids
Published on: September 27, 2024
Reconfigurable fault-tolerant multielectrode array for dependable monitoring of the human brain
Ipsita Acharya1, Bharat Joshi, Bruce Lanning
1Department of Electrical and Computer Engineering, University of North Carolina at Charlotte, NC 29223, USA.
Abstract:
We introduce a fault-tolerant strategy to improve the dependability of a multi-electrode array (MEA), an issue of considerable concern. We propose an interstitial redundancy approach with local reconfiguration. Here spare modules are placed at interstitial sites and can replace neighboring primary modules when they develop faults. We evaluate the performance of such a system under different faults to characterize MEA dependability as a function of redundancy. The results demonstrate that a considerable improvement in MEA dependability can be achieved with a well designed increase in redundancy.
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