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Influence of ventilatory settings on indirect calorimetry in mechanically ventilated patients
S Cecchini1, E Schena, R Cuttone
1Unit of Measurements and Biomedical Instrumentation, Center for Integrated Research, Università Campus Bio-Medico di Roma, 200128 Rome, Italy.
Abstract:
With the aim to assess metabolic monitor's suitability to the use in mechanically ventilated patients, a method, based on the comparison between the measurements performed by the monitor and the ventilator, is here described. In particular, the effects of positive end-expiratory pressure and oxygen inspiratory fraction (FiO(2)) on the metabolic measurements in presence of bias flow are investigated. In this study a metabolic monitor is used to estimate the energy expenditure of 10 mechanically ventilated cardiosurgical patients at different positive end-expiratory pressure, FiO(2) and two different modes of ventilation, with bias flow. The influence of the ventilatory settings on the parameters measured by the monitor is here quantified: a slight decrease of respiratory quotient and a slight increase of resting energy expenditure are observed with the increase of FiO(2). This study shows a good agreement between the measurements of the two devices: FiO(2), expiratory volume (mean difference lower than 3%), and respiratory frequency (mean difference lower than 1%). This also demonstrates the capability of the metabolic monitor to reject the effect of the bias flow.
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