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Updated: May 25, 2026
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Echocardiography Recording in Awake Miniature Pigs
Published on: May 26, 2023
Chronic cuff electrode recordings from walking Göttingen mini-pigs
Mads P Andersen1, Majken Munch, Winnie Jensen
1Neurodan A/S, Sofiendalsvej 85, 9200 Aalborg SV, Denmark. mpa@neurodan.dk.
Summary
Electroneurographic (ENG) signals recorded from nerves during walking in mini-pigs modulated with gait. This method can detect heel strike for foot drop correction systems.
Area of Science:
- Biomedical Engineering
- Neuroscience
- Biomechanics
Background:
- Cuff electrodes are used for nerve recording.
- Gait analysis requires precise timing information.
- Foot drop correction systems need reliable gait phase detection.
Purpose of the Study:
- To investigate the feasibility of using nerve signals for gait phase detection.
- To analyze the modulation of electroneurographic (ENG) signals during walking.
- To assess the potential of ENG signals for controlling functional electrical stimulation (FES) systems.
Main Methods:
- Chronic implantation of cuff electrodes in Göttingen mini-pigs.
- Recording of mixed sensory-/motor nerve activity during walking.
- Signal processing to filter electromyographic (EMG) interference.
- Analysis of the energy content of ENG signals in relation to gait events.
Main Results:
- Successful filtering of electromyographic interference from ENG signals.
- Clear modulation of ENG signal energy content with gait phases.
- Demonstrated potential for detecting heel strike from ENG data.
Conclusions:
- Nerve signal modulation with gait is detectable using cuff electrodes.
- ENG signal analysis offers a viable method for gait phase detection.
- This approach can enhance the control of implantable foot drop correction systems.
