Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices

Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices

Parenteral drug delivery systems play a crucial role in modern therapeutics by enabling the direct administration of drugs into the systemic circulation, bypassing the gastrointestinal tract. These systems are particularly valuable for poorly absorbed oral medications that are unstable in the digestive environment or require rapid onset or sustained therapeutic levels. Delivery is achieved through intravenous, intramuscular, or subcutaneous routes, each selected based on the drug's properties...

Intrauterine Drug Delivery Systems

Intrauterine Drug Delivery Systems

Controlled-release systems for intravaginal and intrauterine drug delivery have been developed primarily for the administration of contraceptive steroid hormones. These delivery routes circumvent first-pass hepatic metabolism, thereby enhancing bioavailability and allowing for reduced systemic dosages compared to oral administration. Such approaches contribute to improved therapeutic efficacy and patient compliance, particularly in long-term contraceptive regimens.Intravaginal Drug Delivery...

Modified-Release Drug Delivery Systems: Rate-Programmed II

Modified-Release Drug Delivery Systems: Rate-Programmed II

Rate-programmed drug delivery systems release drugs in a controlled manner to maintain therapeutic levels. Three main designs include reservoir, matrix, and hybrid systems.Reservoir systems consist of a drug core enclosed within a membrane that controls drug release. In non-swelling reservoir systems, polymers like ethyl cellulose or polymethacrylates are used. These do not hydrate in aqueous media and control release through membrane thickness, porosity, or insolubility. This type includes...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Consensus-based guidelines for research in bracing in idiopathic scoliosis by the SRS comprehensive care committee in collaboration with SOSORT.

Spine deformity·2026

Same author

Quantifying PD1 saturation by PDL1 in tumor tissue using a novel RNA aptamer-based assay.

bioRxiv : the preprint server for biology·2026

Same author

Physiological Impacts of a Newly Discovered Trematode Parasite on Its Host, the Bay Scallop (<i>Argopecten irradians</i>).

Ecology and evolution·2026

Same author

The association between adherence to elective nodal volume guidelines and reduced distant metastasis in esophageal and gastroesophageal junction cancer: a retrospective analysis of elective nodal irradiation.

Journal of gastrointestinal oncology·2026

Same author

Genetic diversity of Apis mellifera filamentous virus in bees sampled in the USA and Jamaica.

Archives of virology·2026

Same author

Therapeutic Hydrogel Microneedle Patch for Burn Wound Field Care.

ACS applied bio materials·2026

Search research articles

Related Experiment Video

Updated: May 25, 2026

High Throughput Microfluidic Rapid and Low Cost Prototyping Packaging Methods

High Throughput Microfluidic Rapid and Low Cost Prototyping Packaging Methods

Published on: December 23, 2013

Ultra-high density packaging technology for injectable medical devices.

Bryan L McLaughlin¹, Brian Smith, John Lachapelle

¹Charles Stark Draper Laboratory, Cambridge, MA 02139, USA.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

|January 19, 2012

Summary

A new ultra-high density packaging platform enables miniaturized implantable medical devices by interconnecting electronic components at the die-level. This innovation achieves unprecedented packaging densities for advanced medical technology.

More Related Videos

3D Microtissues for Injectable Regenerative Therapy and High-throughput Drug Screening

3D Microtissues for Injectable Regenerative Therapy and High-throughput Drug Screening

Published on: October 4, 2017

Simple In-House Ultra-High Performance Capillary Column Manufacturing with the FlashPack Approach

Simple In-House Ultra-High Performance Capillary Column Manufacturing with the FlashPack Approach

Published on: December 4, 2021

Related Experiment Videos

Last Updated: May 25, 2026

High Throughput Microfluidic Rapid and Low Cost Prototyping Packaging Methods

High Throughput Microfluidic Rapid and Low Cost Prototyping Packaging Methods

Published on: December 23, 2013

3D Microtissues for Injectable Regenerative Therapy and High-throughput Drug Screening

3D Microtissues for Injectable Regenerative Therapy and High-throughput Drug Screening

Published on: October 4, 2017

Simple In-House Ultra-High Performance Capillary Column Manufacturing with the FlashPack Approach

Simple In-House Ultra-High Performance Capillary Column Manufacturing with the FlashPack Approach

Published on: December 4, 2021

Area of Science:

Materials Science
Electrical Engineering
Biomedical Engineering

Background:

Future implantable medical devices require significant miniaturization.
Die-level electronics miniaturization and packaging are crucial for advanced medical technology.

Purpose of the Study:

To propose an integrated ultra-high density packaging platform.
To enable a new class of miniaturized medical devices.

Main Methods:

Interconnecting existing Application-Specific Integrated Circuits (ASICs) and discrete components.
Utilizing a novel process for ultra-high density packaging.

Main Results:

Achieved the highest available packaging densities.
Created dense modules for medical device applications.

Conclusions:

The proposed platform is suitable for developing next-generation implantable medical devices.
Ultra-high density packaging is key to advancing medical device miniaturization.