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Ear drops and grommets.

R P Mills1, C Albizzati, A S Todd

  • 1Department of Otolaryngology and Haematology, University of Dundee, Ninewells Hospital, UK.

Clinical Otolaryngology and Allied Sciences
|August 1, 1990
PubMed
Summary
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Ear drops penetrate ventilation tubes differently based on grommet size and surface wetting properties, not viscosity. The displacement technique is crucial for middle ear delivery, especially when grommets are clear of discharge.

Area of Science:

  • Otolaryngology
  • Biomedical Engineering
  • Pharmaceutics

Background:

  • Ventilation tubes (grommets) are used to treat middle ear conditions.
  • Effective delivery of ear drops through grommets is essential for treatment success.
  • Factors influencing ear drop passage through grommets require investigation.

Purpose of the Study:

  • To evaluate the ease of passage of different ear drops through various grommet designs.
  • To determine the relationship between ear drop properties (viscosity, wetting) and penetration.
  • To assess in vivo ear drop penetration during aural discharge using different techniques.

Main Methods:

  • Laboratory model simulating grommet passage with various ear drop preparations.
  • Determination of ear drop viscosities.

Related Experiment Videos

  • In vivo study of ear drop penetration during aural discharge using the displacement technique.
  • Main Results:

    • Significant variation exists in the volume of ear drops needed for grommet penetration.
    • Ease of passage is primarily influenced by grommet size and the preparation's wetting ability.
    • No correlation was found between ear drop viscosity and ease of penetration.
    • In vivo, middle ear penetration was only achieved with the displacement technique.
    • Penetration was more successful when the grommet lumen was free from discharge.

    Conclusions:

    • Grommet size and surface wetting characteristics are key determinants of ear drop penetration.
    • Viscosity does not predict the ease with which ear drops pass through ventilation tubes.
    • The displacement technique is superior for delivering ear drops through grommets, particularly in non-discharging ears.