Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 25, 2026

In vitro Functional Characterization of Mouse Colorectal Afferent Endings
14:09

In vitro Functional Characterization of Mouse Colorectal Afferent Endings

Published on: January 21, 2015

Mapping small intestine bioelectrical activity using high-resolution printed-circuit-board electrodes.

Timothy R Angeli1, Gregory O'Grady, Jonathan C Erickson

  • 1Riddet Institute, New Zealand. tang010@aucklanduni.ac.nz

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
|January 19, 2012
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Potentially-Preventable Deaths Following Colorectal Surgery: A National Retrospective Cohort Study of Surgical Mortality.

ANZ journal of surgery·2026
Same author

Gastric slow-wave morphology in health and disease.

Digestive diseases and sciences·2026
Same author

Hyperactive Intestinal Motility and Postoperative Ileus: The Missing Link?

Diseases of the colon and rectum·2026
Same author

Body Surface Colonic Mapping Detects Meal and Bisacodyl-Induced Colonic Motility in Patients With Chronic Constipation.

The American journal of gastroenterology·2026
Same author

The Clinical Relevance of the Rectosigmoid Brake in Surgical Disorders and Therapies: A Systematic Review of Colonic Manometry Studies.

Neurogastroenterology and motility·2026
Same author

Adolescent Normative Intervals for Body Surface Gastric Mapping: Spectral Analysis.

Neurogastroenterology and motility·2026

Researchers developed new methods for high-resolution in-vivo recording and analysis of small intestine bioelectrical activity using flexible electrode arrays. This technology can improve understanding of gastrointestinal motility in humans.

Area of Science:

  • Gastroenterology
  • Biomedical Engineering
  • Physiology

Background:

  • Understanding small intestine bioelectrical activity is crucial for diagnosing motility disorders.
  • Current methods for recording and analyzing this activity have limitations in resolution and scope.

Purpose of the Study:

  • To develop and validate novel methods for high-resolution, in-vivo recording and analysis of small intestine bioelectrical activity.
  • To automate data analysis for improved efficiency and accuracy.

Main Methods:

  • Flexible printed-circuit-board (PCB) electrode arrays were used for in-vivo recording.
  • Up to 256 simultaneous recordings were performed along the porcine small intestine.
  • The Falling-Edge Variable-Threshold algorithm was automated and tuned for data analysis.

More Related Videos

Bidirectional Electrical and Optoelectronic Interfaces in Healthy and Ischemic Ex Vivo Rat Hearts
08:33

Bidirectional Electrical and Optoelectronic Interfaces in Healthy and Ischemic Ex Vivo Rat Hearts

Published on: July 18, 2025

Performing In Vivo and Ex Vivo Electrical Impedance Myography in Rodents
05:44

Performing In Vivo and Ex Vivo Electrical Impedance Myography in Rodents

Published on: June 8, 2022

Related Experiment Videos

Last Updated: May 25, 2026

In vitro Functional Characterization of Mouse Colorectal Afferent Endings
14:09

In vitro Functional Characterization of Mouse Colorectal Afferent Endings

Published on: January 21, 2015

Bidirectional Electrical and Optoelectronic Interfaces in Healthy and Ischemic Ex Vivo Rat Hearts
08:33

Bidirectional Electrical and Optoelectronic Interfaces in Healthy and Ischemic Ex Vivo Rat Hearts

Published on: July 18, 2025

Performing In Vivo and Ex Vivo Electrical Impedance Myography in Rodents
05:44

Performing In Vivo and Ex Vivo Electrical Impedance Myography in Rodents

Published on: June 8, 2022

Main Results:

  • The automated algorithm achieved 92% sensitivity and 94% positive-predictive value.
  • Slow wave propagation patterns were visualized using automated animations and isochronal maps.
  • High-resolution, multi-location recordings of small intestine bioelectrical activity were achieved.

Conclusions:

  • The developed methods provide a robust platform for studying small intestine bioelectrical activity.
  • These methods are applicable to human studies, offering potential for improved clinical understanding of gastrointestinal motility.
  • Future research can leverage this technology to enhance the diagnosis and management of motility disorders.