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Updated: May 25, 2026

Correlative Microscopy for 3D Structural Analysis of Dynamic Interactions
Published on: June 24, 2013
A correlation and LS-SVM based approach to mitigate motion artifacts in FDK based 3D cone-beam tomography
Ujjal Kumar Bhowmik1, Reza R Adhami
1Department of Electrical and Computer Engineering The University of Alabama in Huntsville Huntsville, AL-35899, USA. ukb0001@uah.edu
Abstract:
Head motion during brain CT studies can degrade the reconstructed image by introducing distortion and loss of resolution, thereby contributing to misdiagnosis of diseases. In this paper, we have proposed a correlation coefficient and Least Squares Support Vector Machines (LS-SVM) based approach to detect and mitigate motion artifacts in FDK based three-dimensional cone-beam tomography. Motion is detected using correlation between adjacent x-ray projections. Artifacts, caused by motion, are mitigated either by replacing motion corrupted projections with their counterpart 180° apart projections under certain conditions, or by estimating motion corrupted projections using LS-SVM based time series prediction. The method has been evaluated on 3D Shepp-Logan phantom. Simulation results validate our claims.
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