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[Expression of MEF2D on nasopharyngeal carcinoma tissues and its influence of prognostic]
Yongling Li1, Longcheng Zhang, Jiang Nong
1Department of Otolaryngology, No. 303 Hospital of PLA, Nanning, China, 530021.
Objective:
To explore the expression of MEF2D in NPC tissues, study the relationship between the expression and prognostic.
Method:
Specimens from 101 NPC patients who were follow-up visited 1 to 7 years were analyzed for MEF2D by using immunohistochemistry.
Result:
(1) The expression of MEF2D was higher in the higher clinical stage. (2) Density and Grey of MEF2D was negative correlated (|r| = 0.865, P < 0.01). (3) NPC patients' survival rate after therapies was 52.5%, the survival curve of 1th clinical stage was higher than 4th. (4) The survival curves of MEF2D stages were no statistical significance.
Conclusion:
There's statistical significance of the MEF2D expression in clinical stages, but not in survival curve, which indicated that MEF2D concerned with invasion and metastatic of NPC.
