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Synthesis and Characterization of an Aspirin-fumarate Prodrug that Inhibits NFκB Activity and Breast Cancer Stem Cells
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Aspirin: from a historical perspective.

Murat Ugurlucan1, Ilker M Caglar, Fatma N Turhan Caglar

  • 1Anadolu Medical Center Hospital, Cardiovascular Surgery Clinic, Turkey. muratugurlucan@yahoo.com

Recent Patents on Cardiovascular Drug Discovery
|January 20, 2012
PubMed
Summary

Aspirin, a widely used pain reliever, has a long history and diverse medical applications. Recent research continues to uncover new uses for acetylsalicylic acid, expanding its therapeutic potential.

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Area of Science:

  • Pharmacology
  • Medical History

Background:

  • Aspirin (acetylsalicylic acid) is one of the oldest and most widely utilized medications globally.
  • Its therapeutic applications span numerous medical disciplines.

Purpose of the Study:

  • To provide a comprehensive review of aspirin's history, pharmacological effects, and diverse clinical uses.
  • To present recent advancements and patents in acetylsalicylic acid interventions.

Main Methods:

  • A thorough literature search was conducted to gather historical and current data on aspirin.
  • Information was compiled from various medical fields to illustrate its broad applicability.

Main Results:

  • Aspirin's utility extends across general medicine, cardiovascular health, neurology, obstetrics and gynecology, dentistry, gastroenterology, and oncology.
  • Recent studies and patents highlight novel pharmaceutical interventions involving acetylsalicylic acid.

Conclusions:

  • Aspirin, with its extensive historical use and varied healing properties, remains a significant therapeutic agent.
  • Ongoing research and emerging applications suggest aspirin will continue to grow in popularity and clinical importance.