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Related Experiment Video

Updated: May 25, 2026

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
18:11

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

Published on: October 1, 2007

Lifting gate polydimethylsiloxane microvalves and pumps for microfluidic control.

Jungkyu Kim1, Minjee Kang, Erik C Jensen

  • 1Department of Chemistry, University of California, Berkeley, California 94720, USA.

Analytical Chemistry
|January 20, 2012
PubMed
Summary

We developed novel pneumatic microvalves and pumps for lab-on-a-chip devices. These "lifting gate" structures offer efficient fluid control and enable integrated sample processing for diverse applications.

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Area of Science:

  • Microfluidics
  • Biotechnology
  • Materials Science

Background:

  • Microfluidic devices require precise fluid control for applications like lab-on-a-chip systems.
  • Existing microvalves and micropumps can be complex to fabricate and integrate.

Purpose of the Study:

  • To develop and characterize novel pneumatically actuated "lifting gate" microvalves and pumps.
  • To demonstrate the integration capabilities of these microfluidic components with various substrates.

Main Methods:

  • Fabrication of fluidic and pneumatic layers using soft-lithography in polydimethylsiloxane (PDMS).
  • Permanent bonding via oxygen plasma treatment and reversible bonding to glass or plastic substrates.
  • Characterization of microvalve break-through pressures and micropump efficiency.

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Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices

Published on: January 27, 2017

Related Experiment Videos

Last Updated: May 25, 2026

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
18:11

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

Published on: October 1, 2007

Bilayer Microfluidic Device for Combinatorial Plug Production
07:03

Bilayer Microfluidic Device for Combinatorial Plug Production

Published on: December 1, 2023

Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices
10:18

Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices

Published on: January 27, 2017

Main Results:

  • Microvalve break-through pressure increased linearly with closing pressure, reaching up to 65 kPa.
  • Micropump efficiency reached up to 86.2%, with controllable nanoliter to microliter volumes.
  • Demonstrated utility in an automated immunoassay for integrated sample processing.

Conclusions:

  • The "lifting gate" microvalve and pump design offers robust and efficient fluidic control.
  • These components facilitate facile integration into diverse lab-on-a-chip platforms.
  • Enables the development of complex microfluidic systems for various applications.