Related Experiment Video
Updated: May 25, 2026
09:42
Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
Published on: August 26, 2014
Video capsule endoscopy in celiac disease: current clinical practice
Pekka Collin1, Emanuele Rondonotti, Knut Ea Lundin
1Department of Gastroenterology and Alimentary Tract Surgery, Medical School, University of Tampere, Tampere, Finland. Pekka.Collin@uta.fi
Journal of Digestive Diseases
|January 20, 2012
Summary
Video capsule endoscopy (VCE) aids in managing refractory sprue by identifying ulcers and strictures. For other celiac disease patients, VCE offers limited clinical impact, primarily guiding dietary compliance.
Area of Science:
- Gastroenterology
- Medical Imaging
Background:
- Video capsule endoscopy (VCE) enables comprehensive visualization of the small intestine.
- Celiac disease diagnosis and management often require detailed small bowel assessment.
Purpose of the Study:
- To evaluate the clinical indications and impact of VCE in managing celiac disease patients.
- To assess VCE findings in both refractory and newly diagnosed celiac disease.
Main Methods:
- A multicenter European study enrolled 84 celiac disease patients on a gluten-free diet who underwent VCE.
- Data on indications, findings, and clinical impact were collected via questionnaire.
- VCE was also performed on 34 treatment-naive celiac disease patients as controls.
Main Results:
- In refractory celiac disease (n=34), VCE revealed abnormalities in 25 patients, including atrophy (8), ulcers (14), and strictures (2).
- VCE guided immunosuppressive treatment adjustments in 9 refractory patients.
- In established celiac disease with less severe symptoms (n=50), VCE showed atrophy (24) and ulcers (3), primarily leading to dietary advice.
- Newly diagnosed celiac disease (n=34) showed atrophy in 30 patients via VCE.
Conclusions:
- VCE significantly impacts the management of refractory sprue, aiding in diagnosis and treatment adjustments.
- For other established celiac disease patients, VCE has a more limited role, mainly reinforcing dietary adherence.
Related Concept Videos
01:28Endoscopic Procedures III: Video Capsule Endoscopy
Capsule endoscopy, or wireless or video capsule endoscopy, is a diagnostic procedure for examining the entire gastrointestinal tract. Patients swallow a capsule about the size of a vitamin tablet. The capsule is equipped with a transmitter, a battery, an LED light source, and a color video camera to capture images throughout the gastrointestinal tract. This procedure is particularly useful for diagnosing conditions such as Crohn's disease, ulcerative colitis, tumors, polyps, ulcers, unexplained...
01:26Endoscopic Procedures V: ERCP
Endoscopic Retrograde Cholangiopancreatography (ERCP) is a diagnostic procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions related to the bile ducts, pancreatic ducts, and gallbladder. This procedure is beneficial for identifying and addressing blockages, gallstones, strictures, and tumors within the biliary or pancreatic systems. ERCP is both diagnostic and therapeutic, offering the ability to visualize and treat identified problems in one session.
Patient...
Patient...
01:29Endoscopic Procedures I: Esophagogastroduodenoscopy
An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:
During an EGD, the endoscope can be used to:
01:26Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy
This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and solid...
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and solid...
01:25Endoscopic Procedures II: Colonoscopy
The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
01:26Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...