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Related Experiment Video

Updated: May 25, 2026

A Modified EPA Method 1623 that Uses Tangential Flow Hollow-fiber Ultrafiltration and Heat Dissociation Steps to Detect Waterborne Cryptosporidium and Giardia spp.
12:11

A Modified EPA Method 1623 that Uses Tangential Flow Hollow-fiber Ultrafiltration and Heat Dissociation Steps to Detect Waterborne Cryptosporidium and Giardia spp.

Published on: July 9, 2012

Targeting Cryptosporidium parvum capture.

Mei Wu1, Helen Bridle, Mark Bradley

  • 1School of Chemistry, University of Edinburgh, West Mains Road, Edinburgh EH9 3JJ, United Kingdom.

Water Research
|January 20, 2012
PubMed
Summary
This summary is machine-generated.

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Researchers screened synthetic polymers to find materials that trap or repel the parasite Cryptosporidium parvum. This discovery aids water treatment and sensor development by understanding protozoan-polymer interactions.

Area of Science:

  • Materials Science
  • Parasitology
  • Biotechnology

Background:

  • Polymer microarrays enable high-throughput screening of materials.
  • Protozoan-polymer interactions are crucial for water treatment and public health.
  • Cryptosporidium parvum is a significant waterborne protozoan parasite.

Purpose of the Study:

  • To investigate protozoan-polymer interactions using a microarray approach.
  • To identify synthetic polymers that interact with Cryptosporidium parvum.
  • To establish structure-function relationships for polymer binding.

Main Methods:

  • Screening of hundreds of synthetic polymers using a microarray platform.
  • Assessment of polymer interactions with viable and non-viable Cryptosporidium parvum oocysts.

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Published on: September 14, 2019

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Last Updated: May 25, 2026

A Modified EPA Method 1623 that Uses Tangential Flow Hollow-fiber Ultrafiltration and Heat Dissociation Steps to Detect Waterborne Cryptosporidium and Giardia spp.
12:11

A Modified EPA Method 1623 that Uses Tangential Flow Hollow-fiber Ultrafiltration and Heat Dissociation Steps to Detect Waterborne Cryptosporidium and Giardia spp.

Published on: July 9, 2012

Studying Cryptosporidium Infection in 3D Tissue-derived Human Organoid Culture Systems by Microinjection
05:31

Studying Cryptosporidium Infection in 3D Tissue-derived Human Organoid Culture Systems by Microinjection

Published on: September 14, 2019

  • Correlation of material properties (composition, wettability, surface chemistry) with binding characteristics.
  • Main Results:

    • Identification of polymers that effectively trap Cryptosporidium parvum.
    • Discovery of polymers that inhibit Cryptosporidium parvum adhesion.
    • Differences observed in adhesion between viable and non-viable oocysts.
    • Established structure-function relationships for polymer-parasite binding.

    Conclusions:

    • Polymer microarrays are effective for studying protozoan-polymer interactions.
    • Identified polymers have potential applications in water purification and filtration.
    • Understanding binding mechanisms can improve water treatment strategies.
    • The study provides a foundation for developing novel sensor materials.