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Updated: May 25, 2026

In Vitro Establishment of a Genetically Engineered Murine Head and Neck Cancer Cell Line using an Adeno-Associated Virus-Cas9 System
Published on: January 9, 2020
Are snoRNAs and snoRNA host genes new players in cancer?
Gwyn T Williams1, Farzin Farzaneh
1Institute for Science and Technology in Medicine, Huxley Building, Keele University, Keele ST5 5BG, UK. g.t.williams@keele.ac.uk
Abstract:
Small nucleolar RNAs (snoRNAs) have long been considered important but unglamorous elements in the production of the protein synthesis machinery of the cell. Recently, however, several independent lines of evidence have indicated that these non-coding RNAs might have crucial roles in controlling cell behaviour, and snoRNA dysfunction could consequently contribute to oncogenesis in previously unsuspected ways.
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