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Updated: May 25, 2026

Manipulation of Ploidy in Caenorhabditis elegans
Published on: March 15, 2018
Is more better? Polyploidy and parasite resistance
K C King1, O Seppälä, M Neiman
1Institute of Integrative Biology, University of Liverpool, Liverpool L69 7ZB, UK. k.king@liverpool.ac.uk
Abstract:
Ploidy-level variation is common and can drastically affect organismal fitness. We focus on the potential consequences of this variation for parasite resistance. First, we elucidate connections between ploidy variation and key factors determining resistance, including allelic diversity, gene expression and physiological condition. We then argue that systems featuring both natural and artificially manipulated ploidy variation should be used to evaluate whether ploidy level influences host-parasite interactions.
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