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QTL Mapping and CRISPR/Cas9 Editing to Identify a Drug Resistance Gene in Toxoplasma gondii
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QTL Mapping and CRISPR/Cas9 Editing to Identify a Drug Resistance Gene in Toxoplasma gondii

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Variation of B1 gene and AF146527 repeat element copy numbers according to Toxoplasma gondii strains assessed using

Jean-Marc Costa1, Stéphane Bretagne

  • 1Laboratoire de Parasitologie-Mycologie, Groupe Hospitalier Chenevier-Mondor, Assistance Publique-Hôpitaux de Paris (APHP), Paris, France.

Journal of Clinical Microbiology
|January 20, 2012
PubMed

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Comparing Copy Number Variations and SNPs02:26

Comparing Copy Number Variations and SNPs

Sequencing of the human genome has opened up several best-kept secrets of the genome. Scientists have identified thousands of genome variations that exist within a population. These variations can be a single nucleotide or a larger chromosomal variation.
Copy number variations or CNVs are the structural variations that cover more than 1kb of DNA sequence. The single nucleotide polymorphism (SNP), on the other hand, is a single nucleotide change or a point mutation that is found in more than 1%...