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Updated: May 25, 2026

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
Published on: January 19, 2016
3,3-Dimethyl-2-benzofuran-1(3H)-one
This study details the crystal structure of a C(10)H(10)O(2) compound, revealing molecular arrangements stabilized by hydrogen bonds and π-π stacking interactions.
Area of Science:
- Crystallography
- Supramolecular Chemistry
Background:
- Understanding molecular packing is crucial in crystal engineering.
- Intermolecular forces dictate solid-state structures and properties.
Purpose of the Study:
- To elucidate the crystal structure and intermolecular interactions of a specific organic compound (C(10)H(10)O(2)).
- To analyze the role of hydrogen bonding and π-π stacking in stabilizing the crystal lattice.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of non-covalent interactions, including hydrogen bonds and π-π stacking, was performed.
Main Results:
- The crystal structure exhibits a crystallographic mirror plane for non-methyl atoms.
- Molecules are organized into zigzag chains via C-H⋯O hydrogen bonds along the [100] direction.
- Weak π-π stacking interactions (3.9817 Å centroid-centroid distance) link these chains along the [010] direction.
Conclusions:
- The crystal packing is governed by a combination of hydrogen bonding and π-π stacking.
- These interactions lead to a robust three-dimensional network in the solid state.
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