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Updated: May 25, 2026

Enhancing Efficiency and Radiolabeling Yields of Carbon-11 Radioligands for Clinical Research Using the Loop Method
Published on: December 20, 2024
1-Hy-droxy-11H-benzo[b]fluoren-11-one
Kew-Yu Chen1, Ming-Jen Chang, Tzu-Chien Fang
1Department of Chemical Engineering, Feng Chia University, 40724 Taichung, Taiwan.
Abstract:
The title compound, C(17)H(10)O(2), is nearly planar, the maximum atomic deviation being 0.053 (2) Å. In the mol-ecule, an intra-molecular O-H⋯O hydrogen bond generates an S(6) ring motif. In the crystal, inversion-related mol-ecules are linked by pairs of weak C-H⋯O hydrogen bonds, forming dimers. π-π stacking is observed in the crystal structure, the closest centroid-centroid distance being 3.7846 (16) Å.
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