Related Experiment Video
Updated: May 25, 2026

06:08
Evaluation of Drug Sorption to PVC- and Non-PVC-based Tubes in Administration Sets Using a Pump
Published on: March 11, 2017
The development of a korean drug dosing database
Sun Ah Kim1, Jung Hoon Kim, Yoo Jin Jang
1Department of Pharmacy, Ewha Womans University Mokdong Hospital, Seoul, Korea.
Healthcare Informatics Research
|January 20, 2012
Summary
A drug dosing database was developed for ethical drugs approved by the Korea Food & Drug Administration (KFDA). This system supports physicians
Area of Science:
- Pharmacology
- Health Informatics
- Drug Information Systems
Background:
- Physicians require accurate medication dosing information to support prescribing decisions.
- Existing drug information systems may lack comprehensive and easily accessible dosing data.
- Development of a specialized drug dosing database is crucial for improving medication safety.
Observation:
- A collaborative effort involving clinicians, pharmacists, KFDA officials, and software developers was undertaken.
- A web-based management program was designed for organized and efficient input of drug dosing information.
- The database structure was refined through iterative analysis, adding relevant fields and removing redundancies.
Findings:
- A comprehensive drug dosing database was successfully created, encompassing 16,994 drugs approved by the KFDA as of July 2009.
- The database excludes specific drug categories like radioactivity drugs and X-ray contrast media.
- The developed system allows for continuous maintenance and updates of dosing information for new drugs.
Implications:
- The drug dosing database will serve as a foundation for developing drug utilization review standards.
- It will enhance the provision of appropriate dosing information to healthcare professionals.
- This resource has the potential to improve prescribing accuracy and patient safety in Korea.
Related Concept Videos
Dosage Regimens: Designs and Approaches
Designing a dosage regimen, which refers to the manner of drug administration, is a complex process involving the selection of drug dose, route, and frequency. This process is underpinned by pharmacokinetic parameters derived from tests and population averages. These parameters are then tailored to patient-specific variables such as diagnosis, demographics, and allergy status. Once therapy commences, therapeutic response monitoring is critical and achieved through clinical and physical...
Dosage Regimens: Partial Pharmacokinetic Parameters
It is not uncommon for complete drug pharmacokinetic profiles to remain elusive in pharmacokinetics. This necessitates certain educated assumptions by pharmacokineticists to determine appropriate dosage regimens without comprehensive pharmacokinetic data from animal or human studies. One prevalent assumption is setting the bioavailability factor, denoted as F, to 1 or 100%. This assumption caters to the scenario where a drug doesn't achieve full systemic absorption, resulting in the patient...
Dosage Regimen Designs: Nomograms and Tabulations
Nomograms and tabulations are vital tools used by clinicians to design accurate and individualized dosage regimens. These instruments provide a straightforward method for adjusting dosages based on individual patient characteristics, including age, weight, and physiological condition. The foundation of a drug's nomogram is population pharmacokinetic data collected and analyzed using specific models. This data simplifies complex equations, presenting them diagrammatically or tabularly for easy...
Dosage Regimen: Individualization
Individualization in dosing regimens is the customization of medication doses for individual patients. Its necessity arises from the goal of maximizing therapeutic benefits while minimizing risks. This approach is pivotal because human responses to drugs can vary widely; what is effective for one person may be inadequate or excessive for another. Interpatient (intersubject) variability refers to differences in drug responses between individuals, while intrapatient (intrasubject) variability...
Drug Dosing: Geriatric Patients
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Drug Dosage Regimen: Overview
A drug dosage regimen describes the specific instructions and schedule for administering a drug to a patient. It considers factors such as drug dosage, frequency, route of administration, and duration of treatment. Designing an appropriate dosage regimen for a patient aims to achieve a target drug concentration at the site of action.
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
