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Canine intravascular lymphoma with overt leukemia
Laura V Lane1, Robin W Allison, Theresa R Rizzi
1Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA. devai@okstate.edu
Veterinary Clinical Pathology
|January 21, 2012
Summary
This study reports the first case of canine intravascular lymphoma, likely originating from Natural Killer (NK) cells, affecting a Labrador Retriever. The lymphoma involved peripheral blood and multiple organs, presenting as generalized weakness.
Area of Science:
- Veterinary Pathology
- Canine Oncology
- Immunohistochemistry
Background:
- Intravascular lymphoma (IVL) is a rare and aggressive neoplastic condition characterized by the proliferation of lymphoid cells within blood vessels.
- Diagnosis of IVL in dogs can be challenging due to its varied clinical presentations and the need for specific diagnostic markers.
- Understanding the cell of origin is crucial for accurate diagnosis and potential therapeutic strategies in canine lymphoma.
