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Procedures for Identifying Infectious Prions After Passage Through the Digestive System of an Avian Species
Published on: November 6, 2013
Oral transmission of L-type bovine spongiform encephalopathy in primate model
Nadine Mestre-Francés1, Simon Nicot, Sylvie Rouland
1Institut National de la Santé et de la Recherche Médicale (INSERM) U710, Montpellier, France. nadine.frances-mestre@univmontp2.fr
Emerging Infectious Diseases
|January 21, 2012
Abstract:
We report transmission of atypical L-type bovine spongiform encephalopathy to mouse lemurs after oral or intracerebral inoculation with infected bovine brain tissue. After neurologic symptoms appeared, transmissibility of the disease by both inoculation routes was confirmed by detection of disease-associated prion protein in samples of brain tissue.
