Related Experiment Video
Updated: May 25, 2026

Evaluation of Vascular Control Mechanisms Utilizing Video Microscopy of Isolated Resistance Arteries of Rats
Published on: December 5, 2017
A conflict between nutritionally adequate diets and meeting the 2010 dietary guidelines for sodium
Matthieu Maillot1, Adam Drewnowski
1Nutritional Sciences Program, School of Public Health, University of Washington, Seattle, USA.
Background:
Compliance with dietary guidelines means incorporating multiple foods and nutrients into everyday diets, to be consumed in smaller or larger amounts. Feasibility studies can help determine whether one nutrient guideline comes into conflict with another. For one half of the U.S. population, the 2010 dietary guidelines for sodium were set at 1500 mg/d.
Purpose:
To test the compatibility of the 1500 mg/day sodium goal with nutrient-adequate diets.
Methods:
Analyses, conducted in 2010, used U.S. federal nutrient composition and dietary intake databases to create modeled food patterns for six gender-age groups using linear programming techniques. The food patterns were designed to meet nutritional standards for 27 nutrients as the mean sodium content was progressively reduced from levels observed in the 2001-2002 National Health and Nutrition Examination Survey (NHANES) down to 1500 mg/day.
Results:
For adults aged <50 years, the 2300 mg/day sodium goal was consistent with nutrient-adequate diets but required large deviations from current eating patterns. The 1500 mg/day goal was not feasible and no mathematical solution was obtained. The lowest-sodium food patterns that were nutrient-adequate and theoretically achievable were very high in fruit juices, nuts, and seeds but were low in grains and meats.
Conclusions:
Compliance with the 2010 sodium guidelines will require large deviations from current eating behaviors and/or a profound modification of the U.S. food supply.
Related Concept Videos
Chronic Kidney Disease III: Interprofessional Care
Heart Failure VI: Adjunct Therapies
Regulation of Sodium and Potassium
Sodium Regulation
Sodium ions make up approximately 90% of extracellular cations, with a normal blood plasma concentration of 136–148 mEq/L. A decrease in blood volume and pressure triggers the release of renin from granular cells in the juxtaglomerular complex (JGC), primarily in...
Disorder of Water Balance
Dehydration
Dehydration occurs when the body loses fluids (particularly water).
Causes:
The major causes of dehydration include excessive sweating, fever, vomiting, diarrhea, and diuresis.
Signs and Symptoms:
Symptoms primarily include intense...
Nursing Diagnosis
The nursing diagnosis focuses on evidence-based...
Responses to Salt Stress