Withholding or withdrawal of life sustaining treatment for newborn infants

Narendra Aladangady1, Laura de Rooy

  • 1Neonatal Unit, Homerton University Hospital NHS Foundation Trust, Homerton Row, London, UK. Narendra.aladangady@homerton.nhs.uk

Early Human Development
|January 21, 2012
PubMed

Insights

With advances in perinatal medicine, withholding or withdrawing life-sustaining treatment may be best for some extremely preterm or sick newborns. This overview guides these difficult decisions, emphasizing palliative care.

Area of Science:

  • Neonatal Medicine
  • Perinatal Care
  • Bioethics

Background:

  • Significant improvements in survival rates for extremely preterm and sick newborns over the past two decades.
  • Despite advances, withholding or withdrawal of life-sustaining treatment remains a consideration for some infants.
  • Ethical and clinical challenges in end-of-life care for critically ill neonates.

Purpose of the Study:

  • To provide an overview of considerations for withholding or withdrawing life-sustaining treatment in neonates.
  • To describe the decision-making process, including factors influencing parental choices and conflict resolution.
  • To outline which treatments may be withheld or withdrawn and emphasize the importance of palliative care.

Main Methods:

  • Literature review on end-of-life care in neonatology.
  • Analysis of ethical guidelines and clinical practices.
  • Synthesis of factors influencing parental decisions and interdisciplinary team communication.

Main Results:

  • Identification of criteria for considering the withholding or withdrawal of life-sustaining treatment.
  • Explanation of the complex decision-making process involving parents, medical teams, and ethical considerations.
  • Emphasis on the necessity of high-quality palliative care following treatment limitation.

Conclusions:

  • Withholding or withdrawing life-sustaining treatment can be in the best interest of some extremely preterm or sick newborns.
  • A structured approach to decision-making, parental involvement, and conflict resolution is crucial.
  • Comprehensive palliative care is essential after the limitation of life-sustaining treatments.

Related Concept Videos

Ethical Issues01:27

Ethical Issues

Nurses are essential in patient care, upholding the ethical principles of their profession and effectively navigating ethical dilemmas. Neglecting ethical issues can lead to inadequate patient care, compromised therapeutic relationships, and moral distress among healthcare workers.
Ethical Concerns in Healthcare:
Ethical Dilemmas I01:17

Ethical Dilemmas I

Ethical dilemmas in nursing are of utmost importance, as they often arise from the tension between adhering to core ethical principles and the practical realities of healthcare delivery. These dilemmas require nurses to navigate complex situations where competing ethical considerations pull them in different directions.
Let us explore some examples to understand the potentially complex moral decisions nurses face.
Take the case of caring for minors, particularly in areas related to reproductive...
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
Nursing Ethical Principles II01:27

Nursing Ethical Principles II

Ethical principles are essential in guiding nurses to fulfill their responsibilities, focusing on the quality of nursing care and decision-making. These principles, including autonomy, beneficence, non-maleficence, justice, and fidelity, shape the ethical framework within healthcare settings.
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's cancer...
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
Methods of reducing fever01:22

Methods of reducing fever

The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever: