Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Paroxysmal non-hereditary angioedema].

J Steurer1, G Siegenthaler-Zuber, W Siegenthaler

  • 1Departement für Innere Medizin, Universitätsspital Zürich.

Deutsche Medizinische Wochenschrift (1946)
|October 19, 1990
PubMed
Summary

This study details recurrent hypovolaemic shock caused by increased capillary permeability, a condition known as capillary leak syndrome. The syndrome presents with severe symptoms and has a poor prognosis despite temporary treatment.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Validity of outcome measures used in randomized clinical trials and observational studies in degenerative lumbar spinal stenosis.

Scientific reports·2023
Same author

Association between depression and anxiety on symptom and function after surgery for lumbar spinal stenosis.

Scientific reports·2022
Same author

Free-ranging wild boar (Sus scrofa) in Switzerland: casual observations and model-based projections during open and closed season for hunting.

Schweizer Archiv fur Tierheilkunde·2020
Same author

[Pain medications for acute and chronic low back pain].

Der Internist·2018
Same author

[Inflammatory muscle diseases (myositis)].

Der Radiologe·2017
Same author

Cost-effectiveness of conservative versus surgical treatment strategies of lumbar spinal stenosis in the Swiss setting: analysis of the prospective multicenter Lumbar Stenosis Outcome Study (LSOS).

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·2017

Area of Science:

  • Internal Medicine
  • Pathophysiology

Background:

  • Recurrent hypovolaemic shock episodes were observed in two previously healthy individuals.
  • The condition manifested with symptoms including limb edema, thirst, sweating, tachycardia, and orthostatic complaints.

Observation:

  • Severe hemodynamic instability occurred, with marked drops in blood pressure and elevated heart rates.
  • Significant hemoconcentration was noted, indicated by high hematocrit and hemoglobin levels.
  • Temporary improvement was achieved with plasma expanders, but symptoms recurred.

Findings:

  • The underlying cause identified was increased permeability of tissue capillaries.
  • Renal, pulmonary, and cerebral vasculature appeared unaffected.
  • Pharmacological interventions (ketotifen and gingko biloba extract) showed limited long-term efficacy.

Related Experiment Videos

Implications:

  • Capillary leak syndrome is a serious condition with a poor prognosis.
  • Further research is needed to identify effective long-term treatments.
  • Early diagnosis and management are crucial for patients with recurrent hypovolaemic shock.