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Published on: March 28, 2025
Acute aortic dissection at two extreme ages
A R M Ramzisham1, H Arief, K S Ngoo
1Division of Cardiothoracic Surgery, Heart and Lung Centre, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaakob Latif, Cheras, Kuala Lumpur, Malaysia. drramzi@ymail.comm.my
Insights
Acute aortic dissection is a serious medical emergency requiring immediate care. This study shares successful management experiences in patients at the extreme age ranges, highlighting improved outcomes.
Area of Science:
- Cardiovascular Medicine
- Vascular Surgery
- Critical Care Medicine
Background:
- Acute aortic dissection is a life-threatening emergency with high mortality rates if untreated.
- Prompt diagnosis and multidisciplinary management involving medical, surgical, and intensive care are crucial.
- Aortic rupture is the primary cause of death in untreated acute aortic dissection.
Observation:
- This study presents successful management experiences in acute aortic dissection cases across a wide age spectrum.
- The cases highlight successful interventions in patients at the two extreme age ranges.
- A comprehensive literature review on pathogenesis is included.
Findings:
- Successful management strategies were identified for acute aortic dissection in elderly and pediatric patients.
- The study demonstrates the feasibility of positive outcomes even in extreme age groups.
- Pathogenesis and treatment considerations specific to different age groups were discussed.
Implications:
- These findings suggest that prompt and tailored multidisciplinary care can lead to successful outcomes in acute aortic dissection, irrespective of patient age.
- The study provides valuable insights for managing acute aortic dissection in diverse patient populations.
- Further research into age-specific treatment protocols may optimize patient survival rates.
Abstract:
Acute aortic dissection is a life-threatening condition, warranting prompt diagnosis and treatment. Management of which incorporates multidisciplinary expertise from the medical, surgical and intensive care. If left untreated, the mortality rate of acute aortic disease exceeds 50% within 48 hours and 80% within two weeks, with a 5-year survival rate of 19%. The most common cause of death in untreated acute aortic dissection, regardless of aetiology, is aortic rupture. We would like to share our successful experience of cases at the two extreme ages of acute aortic dissection. Literature review with their pathogenesis are discussed.
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