Aortic Valve Replacement for Aortic Stenosis and Concomitant Coronary Artery Bypass: Long-term Outcomes and

Won-Chul Cho1, Dong-Gon Yoo, Joon-Bum Kim

  • 1Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan College of Medicine, Korea.

Insights

Coronary artery bypass grafting (CABG) with aortic valve replacement (AVR) for aortic stenosis shows acceptable surgical outcomes. Key predictors of mortality include patient age, reduced glomerular filtration rate (GFR), and left ventricular (LV) mass.

Area of Science:

  • Cardiovascular Surgery
  • Cardiac Surgery Outcomes
  • Aortic Stenosis Management

Background:

  • Aortic stenosis frequently necessitates aortic valve replacement (AVR).
  • Coronary artery disease (CAD) often coexists with aortic stenosis.
  • Combined AVR and coronary artery bypass grafting (CABG) is a complex surgical procedure.

Purpose of the Study:

  • To evaluate surgical results of combined AVR and CABG for aortic stenosis.
  • To identify predictors of long-term survival in these patients.
  • To assess the safety and efficacy of this combined surgical approach.

Main Methods:

  • Retrospective analysis of 183 patients undergoing combined AVR and CABG for aortic stenosis (1990-2009).
  • Mean follow-up of 59.8 months with 98.3% follow-up completion.
  • Cox regression analysis used to determine mortality predictors.

Main Results:

  • Low in-hospital mortality rate of 2.7% (5 patients).
  • Long-term survival rates of 91.5% (1 year), 74.8% (5 years), and 59.6% (10 years).
  • Significant mortality predictors identified: advanced age, GFR < 60 mL/min, and increased left ventricular (LV) mass.

Conclusions:

  • Combined AVR and CABG for aortic stenosis and CAD yields acceptable surgical outcomes.
  • Patient age, impaired renal function (GFR < 60 mL/min), and LV mass are critical determinants of long-term survival.
  • Risk stratification using these factors can aid in patient management.
Abstract

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