[Cost-effectiveness analysis of integrated control strategy of parasitic diseases in demonstration plots]

To study the cost-effectiveness of different deworming schemes in demonstration plots of integrated control of parasitic diseases.

The cost-effectiveness was analyzed between mass drug administration and drug administration to focal population according to the different infection rates of parasites.

In the demonstration plots of soil-born nematodes control, the costs for reducing one infected case and the cost for reducing 1% infection rate per ten thousand people in mass drug administration groups (Group 1 and Group 2) and drug administration to focal population were 20.73, 14.42 Yuan and 14.33 Yuan, and 1 700.49, 1 503.19 Yuan and 145.41 Yuan, respectively. In the demonstration plots of control of clonorchiasis sinensis, the costs for reducing one infected case and the cost for reducing 1% infection rate per ten thousand people in mass drug administration group and drug administration to focal population were 31.03 Yuan and 37.01 Yuan, and 3 115.10 Yuan and 3841.38 Yuan, respectively. The multiple effectiveness indexes for control of soil-transmitted nematodes in the mass drug administration groups (Group 1 and Group 2) and drug administration to focal population were 76.72, 80.27 and 97.64, respectively. The multiple effectiveness indexes for control of clonorchiasis sinensis in the mass drug administration group and the drug administration to focal population group were 112.93 and 65.49, respectively.

We should choose the deworming schemes not only to get a great reduction of human parasite infection rate and a rapid effective reduction of the source of infection, but also to make a full use of the limited funds on target population.