Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

An implantable neurocybernetic prosthesis system.

R Terry1, W B Tarver, J Zabara

  • 1Cyberonics, Inc., Webster, TX 77598-4135.

Epilepsia
|January 1, 1990
PubMed
Summary

The neurocybernetic prosthesis, an implantable device, delivers electrical signals to the vagus nerve to reduce epileptic seizures. Design modifications have addressed earlier electrode breakage issues, improving device reliability.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Review: What innovations in pain measurement and control might be possible if we could quantify the neuroimmune synapse?

Animal : an international journal of animal bioscience·2019
Same author

Axial Multicentric Osteosarcoma in an English Cocker Spaniel.

Journal of veterinary internal medicine·2016
Same author

Physiotherapy management of joint hypermobility syndrome--a focus group study of patient and health professional perspectives.

Physiotherapy·2015
Same author

Lactation estrus induction in multi- and primiparous sows in an Australian commercial pork production system.

Journal of animal science·2014
Same author

Is lavender an anxiolytic drug? A systematic review of randomised clinical trials.

Phytomedicine : international journal of phytotherapy and phytopharmacology·2012
Same author

Examination of subfamilial phylogeny in Bromeliaceae using comparative sequencing of the plastid locus ndhF.

American journal of botany·2011

Area of Science:

  • Biomedical Engineering
  • Neuroscience
  • Medical Devices

Background:

  • Epileptic seizures pose significant challenges to patient quality of life.
  • Existing treatments for epilepsy have limitations, necessitating novel therapeutic approaches.
  • The vagus nerve is a potential target for neuromodulation therapies.

Purpose of the Study:

  • To evaluate the safety and efficacy of the neurocybernetic prosthesis for epilepsy management.
  • To describe the implantation and programming procedures for the device.
  • To assess the impact of design modifications on device performance.

Main Methods:

  • Implantation of the neurocybernetic prosthesis in a subcutaneous chest pocket.
  • Delivery of constant current electrical signals to the vagus nerve via a stimulation lead.
  • Programming of the device using an IBM-compatible personal computer and programming wand.

Main Results:

  • The neurocybernetic prosthesis demonstrated potential in reducing seizure frequency and/or severity.
  • Initial electrode breakage was observed in early patient groups.
  • Subsequent design modifications appear to have resolved the electrode breakage issue.

Conclusions:

  • The neurocybernetic prosthesis is a viable option for epilepsy treatment.
  • Ongoing device development has addressed critical component failures.
  • Further research is warranted to fully establish long-term efficacy and safety.

Related Experiment Videos