Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Depressive Disorders: Etiology

Depressive Disorders: Etiology

Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...

Depression: Overview

Depression: Overview

Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...

Long-term Depression

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.

Long-term Depression

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over time, all...

Stress and Mental Health

Stress and Mental Health

Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...

Depressive Disorders: MDD and Dysthymia

Depressive Disorders: MDD and Dysthymia

Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Social anxiety disorder in Canada: sociodemographic and psychosocial correlates.

Psychiatry research·2026

Same author

Exploring the experiences, challenges, and coping strategies of caregivers of women with Ovarian Cancer: A scoping review.

PloS one·2026

Same author

Casting a long shadow: Exploring the link between childhood maltreatment and cancer in adulthood.

PloS one·2026

Same author

Longitudinal associations between changes in employment status and depressive symptoms during the early COVID-19 pandemic: evidence from the Canadian Longitudinal Study on Aging (CLSA).

Health promotion and chronic disease prevention in Canada : research, policy and practice·2026

Same author

Flourishing older Canadians: What characteristics are associated with complete mental health?

PloS one·2026

Same author

Darvadstrocel in Patients With Crohn's Disease With Complex Perianal Fistulas: The ADMIRE CD II Phase 3 Randomized Trial.

Gastroenterology·2026

Search research articles

Related Experiment Video

Updated: May 25, 2026

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

Published on: May 22, 2019

The association between depression, suicidal ideation, and stroke in a population-based sample.

Esme Fuller-Thomson¹, Maressa J Tulipano, Michael Song

¹Factor-Inwentash Faculty of Social Work, University of Toronto, Toronto, ON, Canada. esme.fuller.thomson@utoronto.ca

International Journal of Stroke : Official Journal of the International Stroke Society

|January 24, 2012

Summary

Stroke survivors have higher rates of depression and suicidal ideation. Early screening is crucial, especially for those with physical limitations, to improve mental health outcomes.

More Related Videos

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Published on: April 26, 2024

Related Experiment Videos

Last Updated: May 25, 2026

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

Published on: May 22, 2019

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Published on: April 26, 2024

Area of Science:

Neurology
Psychiatry
Public Health

Background:

Post-stroke depression and suicidal ideation are significant concerns for survivors.
Understanding the prevalence and risk factors is vital for effective intervention.

Purpose of the Study:

To determine the frequency of depression and suicidal ideation in stroke survivors compared to non-stroke individuals.
To identify demographic factors associated with increased odds of depression and suicidal ideation post-stroke.

Main Methods:

Secondary analysis of the Canadian Community Health Survey, a population-based dataset.
Logistic regression models were employed to analyze depression and suicidal ideation rates.

Main Results:

Stroke survivors showed significantly higher rates of depression (7.4%) and suicidal ideation (15.2%) compared to controls.
Adjusted analyses revealed stroke survivors had double the odds of depression and suicidal ideation.
Functional limitations substantially decreased the observed association, with younger Caucasians showing higher odds.

Conclusions:

Regular screening for depression and suicidal ideation is essential for stroke survivors.
Particular attention should be given to survivors experiencing substantial physical limitations.