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Warfarin induced skin necrosis in a patient with craniopharyngioma
Mohammad H Bhat1, Sanjay Bhadada, Anil Bhansali
1Department of Endocrinology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Abstract:
Oral anticoagulants are associated with several adverse skin manifestations ranging from ecchymosis, purpura, and hemorrhagic necrosis to maculopapular rash, vesicular urticarial eruptions and purple toes. Skin necrosis is a rare but serious side effect of warfarin therapy, associated with significant morbidity and mortality. The prevalence of warfarin induced skin necrosis (WISN) is 0.01-0.1%. We report a 20-year-old female patient of craniopharyngioma who developed WISN following postoperative femoropopliteal deep vein thrombosis.
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