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A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...

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Related Experiment Video

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Retroductal Submandibular Gland Instillation and Localized Fractionated Irradiation in a Rat Model of Salivary Hypofunction
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Submandibular space abscess: a clinical trial for testing a new technique.

Mojtaba Mohamadi Ardehali1, Mehrdad Jafari, Ali Bagheri Hagh

  • 1Tehran University of Medical Sciences, Tehran, Iran.

Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
|January 24, 2012
PubMed
Summary

This study compared intraoral drainage with external approaches for submandibular space abscesses. The intraoral method offers better cosmetic outcomes and simpler postoperative care without compromising treatment efficacy.

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Area of Science:

  • Oral and Maxillofacial Surgery
  • Surgical Innovation
  • Abscess Management

Background:

  • Submandibular space abscesses traditionally require external drainage.
  • External approaches can lead to visible scarring and complex wound care.
  • Minimally invasive techniques are sought to improve patient outcomes.

Purpose of the Study:

  • To compare the efficacy and outcomes of intraoral drainage versus external cervical drainage for submandibular space abscesses.
  • To evaluate cosmetic results and postoperative complications associated with each approach.

Main Methods:

  • A randomized clinical trial involving 40 patients with submandibular abscesses.
  • Patients were randomized to either an intraoral drainage group or a classic external cervical drainage group.
  • Data collected included hospitalization duration, antibiotic use, scar formation, and nerve injury.

Main Results:

  • No significant differences were observed in postoperative hospitalization or intravenous antibiotic duration between the groups.
  • The intraoral approach group experienced no marginal mandibular nerve weakness or skin scarring.
  • Both methods demonstrated comparable efficacy in treating submandibular abscesses.

Conclusions:

  • Intraoral drainage is a viable and potentially superior option for selected submandibular abscess cases.
  • This minimally invasive technique offers improved cosmetic results and simplified postoperative wound management.
  • The intraoral approach may reduce the risk of injury to surrounding nerves compared to external methods.