Inhibition of adenosine 3',5'-monophosphate-dependent protein kinase by staphylococcal alpha-toxin

Staphylococcal alpha-toxin inhibited the activity of cyclic adenosine 3',5'-monophosphate-dependent protein kinase by competitive inhibition, probably by its interaction with a cyclic adenosine 3',5'-monophosphate-binding site in the protein kinase molecule.