Related Experiment Video
Updated: May 25, 2026
Using a 1064-nm Picosecond Neodymium-Doped Yttrium Aluminum Garnet Laser for Periorbital Hyperpigmentation
Published on: May 23, 2025
Long-pulsed 1064-nm Nd:YAG laser significantly improves keratosis pilaris: a randomized, evaluator-blind study
Pichai Saelim1, Marisa Pongprutthipan, Suwimon Pootongkam
1Department of Medicine, Division of Dermatology, Chulalongkorn University, Faculty of Medicine, Bangkok, Thailand.
Background:
Keratosis pilaris (KP) is a very common disorder; yet, very few treatment options are available.
Objectives:
To evaluate the efficacy of long-pulsed 1064-nm Nd:YAG laser for the treatment of KP.
Materials And Methods:
Eighteen patients with untreated KP on the upper outer arms were enrolled in a randomized clinical trial. One arm was treated with long-pulsed 1064-nm Nd:YAG laser at 30 msec pulse width and fluence of 34 J/cm(2), while the contralateral arm served as control. Patients received three consecutive treatments at 4-week intervals. Three blinded dermatologists assessed digital photographs using a quartile grading system to separately rate global improvement, erythema and the number of keratotic papules.
Results:
Seventeen patients completed the study. There were statistically significant improvements in global assessment, erythema and the number of keratotic papules at 4 weeks after the last treatment (p < 0.05). All patients also stated that their lesions improved and were satisfied with the laser treatment.
Conclusion:
Long-pulsed 1064-nm Nd:YAG laser has been shown to improve KP in Thai patients compared with control after three treatment sessions.
