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Related Experiment Video

Updated: May 25, 2026

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries

Published on: March 31, 2021

Nonfluoride caries-preventive agents: new guidelines.

Frieda Atherton Pickett¹

¹Graduate Dental Hygiene Division Idaho State University, Pocatello, ID, UDA. fpickett2@gmail.com

The Journal of Contemporary Dental Practice

|January 25, 2012

Summary

This summary is machine-generated.

Certain nonfluoride caries-prevention agents offer benefits as add-on therapies for individuals at higher risk of cavities. These agents should supplement primary prevention strategies like fluoride and sealants.

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Area of Science:

Dental science
Preventive dentistry
Caries research

Background:

Nonfluoride caries-prevention agents are increasingly available.
Evidence-based decision-making is crucial for oral healthcare professionals.
The American Dental Association (ADA) Council on Scientific Affairs reviewed these agents.

Purpose of the Study:

To evaluate the efficacy of nonfluoride agents in preventing and managing caries.
To develop clinical recommendations for the use of nonfluoride agents.
To inform oral healthcare professionals on evidence-based practices.

Main Methods:

A systematic review was conducted by an expert panel.
Recommendations were developed based on the review findings.
Levels of evidence certainty and clinical applications were discussed.

Main Results:

Nonfluoride agents were found to be beneficial as adjuncts to primary prevention.
Primary prevention includes fluoride, sealants, and dietary modifications.
All reviewed nonfluoride agents should be used as supplementary treatments.

Conclusions:

Certain nonfluoride agents may offer adjunctive benefits for caries prevention.
These benefits are particularly noted in children and adults with higher caries risk.
The findings support the use of nonfluoride agents as part of a comprehensive caries management plan.