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Topical tretinoin research: an historical perspective
1R.W. Johnson Pharmaceutical Research Institute, Raritan, New Jersey 08869-0602.
The Journal of International Medical Research
|January 1, 1990
Summary
Topical tretinoin, a vitamin A derivative, effectively treats acne and improves skin quality. Further studies confirmed its efficacy in reducing wrinkles and hyperpigmentation associated with photodamaged skin.
Area of Science:
- Dermatology
- Dermatological Therapy
Background:
- Topical tretinoin, a vitamin A derivative, was first recognized for its dermatological potential nearly 30 years ago.
- Initial research focused on its efficacy in treating various skin disorders, notably acne, establishing it as a fundamental treatment.
- Observations of skin quality improvement in elderly acne patients led to further investigation into its effects on photodamaged skin.